Worming toward Transdifferentiation, One (Epigenetic) Step at a Time

Ergin Beyret, Juan Carlos Izpisua Belmonte*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

Manipulation of cellular identity in the laboratory is generally inefficient due to stochastic events, including epigenomic alterations. Recently in Science, Zuryn etal. (2014) demonstrate that the efficiency of a naturally occurring transdifferentiation event in Caenorhabditis elegans is ensured through stepwise epigenetic modifications during specific phases of lineage conversion.

Original languageEnglish (US)
Pages (from-to)641-642
Number of pages2
JournalDevelopmental Cell
Volume30
Issue number6
DOIs
StatePublished - Sep 29 2014

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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