Visible-light photoredox catalyzed synthesis of pyrroloisoquinolines via organocatalytic oxidation/ [3 + 2] cycloaddition/oxidative aromatization reaction cascade with Rose Bengal

Carlos Vila, Jonathan Lau, Magnus Rueping*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Pyrrolo[2,1-a]isoquinoline alkaloids have been prepared via a visible light photoredox catalyzed oxidation/[3 + 2] cycloaddition/ oxidative aromatization cascade using Rose Bengal as an organo-photocatalyst. A variety of pyrroloisoquinolines have been obtained in good yields under mild and metal-free reaction conditions.

Original languageEnglish (US)
Pages (from-to)1233-1238
Number of pages6
JournalBeilstein Journal of Organic Chemistry
Volume10
DOIs
StatePublished - May 27 2014

Keywords

  • Alkaloids
  • Organocatalysis
  • Oxidation
  • Photochemistry
  • Photoredox catalysis
  • Rose Bengal
  • Visible-light

ASJC Scopus subject areas

  • Organic Chemistry

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