Visible-light photoredox-catalyzed synthesis of nitrones: Unexpected rate acceleration by water in the synthesis of isoxazolidines

Hong Hou, Shaoqun Zhu, Fangfang Pan, Magnus Rueping*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

A new oxidative [3 + 2] cycloaddition of N-substituted hydroxylamines with alkenes was established under visible light photoredox catalysis. This novel protocol provides a rapid, mild, and efficient access to valuable five-membered ring isoxazolidine heterocycles in a concise fashion.

Original languageEnglish (US)
Pages (from-to)2872-2875
Number of pages4
JournalOrganic Letters
Volume16
Issue number11
DOIs
StatePublished - Jun 6 2014

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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