Visible light photoredox-catalysed intermolecular radical addition of α-halo amides to olefins

Masaki Nakajima, Quentin Lefebvre, Magnus Rueping*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

We present α-chloro amides as a new class of α-acetyl radical precursors, which undergo a tin-free, photoredox-catalysed intermolecular α-alkylation with various olefins exclusively in an anti-Markovnikov fashion. The reaction represents a reductive atom transfer radical addition (ATRA) and provides a series of alkylated amides in good yields. This journal is

Original languageEnglish (US)
Pages (from-to)3619-3622
Number of pages4
JournalChemical Communications
Volume50
Issue number27
DOIs
StatePublished - Apr 7 2014

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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