VIP neurons in the cerebral cortex

Pierre Magistretti*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

VIP-containing cells in the neocortex are intrinsic neurons of the bipolar type, which release VIP through mechanisms that involve Ca2+ and lipoxygenase metabolites. VIP receptors are coupled to cAMP-generating systems that are amplified by various neurotransmitters such as noradrenaline, histamine and GABA. Pierre Magistretti reviews the evidence that VIP neurons play an important role in the local regulation of metabolism in the cerebral cortex by stimulating glycogenolysis and altering cortical blood flow.

Original languageEnglish (US)
Pages (from-to)250-254
Number of pages5
JournalTrends in Pharmacological Sciences
Volume11
Issue number6
DOIs
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Pharmacology
  • Toxicology

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