Nekotorye osobennosti évoliutsii povtorov Alu mlekopitaiushchikh.

Translated title of the contribution: Various aspects of evolution of Alu repeats in mammals

N. A. Kolchanov*, I. A. Shakhmuradov, V. V. Kapitonov, L. V. Omel'ianchuk

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A complex study on various evolutionary peculiarities of the mammalia dispersed Alu repeats (Alu repeats of primates and B1 of rodents) has been carried out by phylogenetic analysis. A phylogenetic tree, containing the 7SL RNA genes and the Alu repeats of primates and rodents has been constructed. It has been shown that the branch of the phyletic line leading to the Alu repeats of primates and B1 of rodents from the 7SL RNA genes occurred after the divergence of the 7SL RNA genes of amphibia and mammalia, but before the divergence of the 7SL RNA genes of primates and rodents (250.10 years ago). A statistically reliable slowing down in the evolutionary rates of one of two monomers for the human Alu repeats has been proved. It may be caused by the functional load of the corresponding monomer in connection with the presence of a definit regulatory site in it.

Translated title of the contributionVarious aspects of evolution of Alu repeats in mammals
Original languageRussian
Pages (from-to)1335-1344
Number of pages10
JournalMolekulyarnaya Biologiya
Volume22
Issue number5
StatePublished - Sep 1 1988

ASJC Scopus subject areas

  • Medicine(all)

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