Using cyber-infrastructure for dynamic data driven laser treatment of cancer

C. Bajaj*, J. T. Oden, K. R. Diller, J. C. Browne, J. Hazle, I. Babuška, J. Bass, L. Bidaut, L. Demkowicz, A. Elliott, Y. Feng, D. Fuentes, B. Kwon, S. Prudhomme, R. J. Stafford, Y. Zhang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

Hyperthermia based cancer treatments are used to increase the susceptibility of cancerous tissue to subsequent radiation or chemotherapy treatments, and in the case in which a tumor exists as a well-defined region, higher intensity heat sources may be used to ablate the tissue. Utilizing the guidance of real-time treatment data while applying a laser heat source has the potential to provide unprecedented control over the outcome of the treatment process [6,12]. The goals of this work are to provide a working snapshot of the current system architecture developed to provide a real-time finite element solution of the problems of calibration, optimal heat source control, and goal-oriented error estimation applied the equations of bioheat transfer and demonstrate that current finite element technology, parallel computer architecture, peer-to-peer data transfer infrastructure, and thermal imaging modalities are capable of inducing a precise computer controlled temperature field within the biological domain.

Original languageEnglish (US)
Title of host publicationComputational Science - ICCS 2007 - 7th International Conference, Proceedings, Part I
Pages972-979
Number of pages8
Volume4487 LNCS
StatePublished - 2007
Externally publishedYes
Event7th International Conference on Computational Science, ICCS 2007 - Beijing, China
Duration: May 27 2007May 30 2007

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4487 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other7th International Conference on Computational Science, ICCS 2007
CountryChina
CityBeijing
Period05/27/0705/30/07

ASJC Scopus subject areas

  • Computer Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Theoretical Computer Science

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