Use of photopatterned nanoporous polymer monoliths as passive mixers to enhance mixing efficiency for on-chip labeling reactions

D. A. Mair, E. Geiger, T. Schwei, T. Dinio, J. Fréchet, F. Svec

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

A passive micromixer was prepared by photopatterning a periodic arrangement of nanoporous polymer monolith (nPPM) structures directly within the channel of a plastic microfluidic chip. By optimizing the composition of the polymerization solution and irradiation time we demonstrate the ability to fabricate nPPM in regular 100 μm segments. By monitoring laser-induced fluorescence (LIF) of reaction products we found this photopatterned array to have the highest mixing efficiency when compared to an equivalent length of continuous segment plug of nPPM and an open channel. These results indicate that the regularly spaced open areas between the plugs of nPPM enhances mixing efficiency.

Original languageEnglish (US)
Title of host publication12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference
PublisherChemical and Biological Microsystems Society
Pages1399-1401
Number of pages3
StatePublished - 2008
Externally publishedYes
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: Oct 12 2008Oct 16 2008

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period10/12/0810/16/08

Keywords

  • Chip
  • Passive micromixer
  • Photopattern
  • Porous polymer monolith

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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