Tunable mechanical properties of ultrasmall peptide hydrogels by crosslinking and functionalization to achieve the 3D distribution of cells

Wei Yang Seow, Charlotte Hauser*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

A disulfide-crosslinked hydrogel made from ultrasmall peptides is introduced. Crosslinked gels are more elastic and better able to maintain shape integrity. Using facile chemistry, RGD (or other bioactive signals) can be conjugated onto the peptide fibers. Gels formed are biocompatible and support the three-dimensional distribution of cells.

Original languageEnglish (US)
Pages (from-to)1219-1223
Number of pages5
JournalAdvanced Healthcare Materials
Volume2
Issue number9
DOIs
StatePublished - Sep 1 2013

Keywords

  • 3D environment
  • Crosslinking
  • Disulfide bonds
  • Hydrogel
  • Ultrasmall peptides

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Pharmaceutical Science

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