TiPs: a database of therapeutic targets in pathogens and associated tools.

Rosalba Lepore, Anna Tramontano, Allegra Via

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

MOTIVATION: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. AVAILABILITY AND IMPLEMENTATION: The TiPs database is freely available at http://biocomputing.it/tips. CONTACT: anna.tramontano@uniroma1.it or allegra.via@uniroma1.it.
Original languageEnglish (US)
Pages (from-to)1821-1822
Number of pages2
JournalBioinformatics
Volume29
Issue number14
DOIs
StatePublished - May 21 2013
Externally publishedYes

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