Tin-free visible light photoredox catalysed cyclisation of enamides as a mild procedure for the synthesis of γ-lactams

Eleonora Fava, Masaki Nakajima, Martin B. Tabak, Magnus Rueping

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The first visible light mediated tin-free cyclisation of α-chloroenamides leading to the synthesis of substituted γ-lactams with excellent stereoselectivity is reported. The protocol employs the single-electron reduction of activated C–Cl bonds, which are typically inert towards reduction.
Original languageEnglish (US)
Pages (from-to)4531-4535
Number of pages5
JournalGreen Chem.
Volume18
Issue number16
DOIs
StatePublished - 2016

Fingerprint Dive into the research topics of 'Tin-free visible light photoredox catalysed cyclisation of enamides as a mild procedure for the synthesis of γ-lactams'. Together they form a unique fingerprint.

Cite this