Theoretical morphology of developmental asymmetries

Diego Rasskin-Gutman*, Juan Carlos Izpisúa-Belmonte

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Morphospaces are theoretical tools to explore the morphological organization of living and fossil organisms. They have been used mostly by the paleontological community in an effort to get the most out of one of the only pieces of evidence that fossil material usually provide: the morphology of hard parts. The expectation with the establishment of theoretical morphospaces is that, by abstracting and modeling the fundamental parts of form, the multiple processes that generate the phenotypes of embryonic and adult structures will be better understood. In this essay, we suggest that ontogenetic trajectories can be used as the generative functions that build morphospaces, and propose approaches to build theoretical models for the establishment of left-right asymmetries during vertebrate heart embryogenesis.

Original languageEnglish (US)
Pages (from-to)405-412
Number of pages8
JournalBioEssays
Volume26
Issue number4
DOIs
StatePublished - Apr 2004
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Biochemistry
  • Cell Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Agricultural and Biological Sciences (miscellaneous)
  • Plant Science

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