Theoretical and experimental study of electroporation of red blood cells using MEMS technology

Peigang Deng, Guangyao Yin, Tong Yi Zhang, Donald C. Chang, Yi-Kuen Lee

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2 Scopus citations

    Abstract

    A theoretical and experimental study of electroporation (EP) of red blood cells (RBCs) was presented in this paper. With additional strain energy, an energy-based model of an electropore induced on a RBC's membrane at different electric fields was proposed to predict the critical EP electric field strength. In addition, EP experiments with red blood cells at single-cell level was carried out on a micro EP chip. The measured critical EP electric field strengths are in agreement with the numerical predictions. ©2010 IEEE.
    Original languageEnglish (US)
    Title of host publication2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems
    PublisherInstitute of Electrical and Electronics Engineers (IEEE)
    Pages595-598
    Number of pages4
    ISBN (Print)9781424465439
    DOIs
    StatePublished - Jan 2010

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