The plant homologue of MAP kinase is expressed in a cell cycle-dependent and organ-specific manner

Claudia Jonak, Aniko Páy, Laszlo Bögre, Heribert Hirt*, Erwin Heberle-Bors

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

92 Scopus citations

Abstract

In animals, MAP kinase plays a key role in growth factor-stimulated signalling and in mitosis. The isolation of a Medicago sativa cDNA clone MsK7 which shows 52% identity to animal MAP kinases is reported. The deduced protein sequence shows all the important structural features of MAP kinases and also contains the highly conserved Thr-183 and Tyr-185 residues. Northern analysis of synchronized alfalfa cells showed that the MsK7 kinase gene is expressed at low levels in G1 phase but at higher levels in S and G2 phases of the cell cycle. In the plant, only stems and roots were found to contain MAP kinase MsK7 mRNA. Southern and PCR analyses indicated that alfalfa contains at least four highly related MAP kinase genes.

Original languageEnglish (US)
Pages (from-to)611-617
Number of pages7
JournalPlant Journal
Volume3
Issue number4
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Genetics
  • Plant Science
  • Cell Biology

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