TY - JOUR
T1 - The genome of Chenopodium quinoa
AU - Jarvis, David Erwin
AU - Shwen, Ho
AU - Lightfoot, Damien
AU - Schmöckel, Sandra M.
AU - Li, Bo
AU - Borm, Theo J. A.
AU - Ohyanagi, Hajime
AU - Mineta, Katsuhiko
AU - Michell, Craig
AU - Saber, Noha
AU - Kharbatia, Najeh M.
AU - Rupper, Ryan R.
AU - Sharp, Aaron R.
AU - Dally, Nadine
AU - Boughton, Berin A.
AU - Woo, Yong
AU - Gao, Ge
AU - Schijlen, Elio G. W. M.
AU - Guo, Xiujie
AU - Momin, Afaque Ahmad Imtiyaz
AU - Negrão, Sónia
AU - Al-Babili, Salim
AU - Gehring, Christoph A
AU - Roessner, Ute
AU - Jung, Christian
AU - Murphy, Kevin
AU - Arold, Stefan T.
AU - Gojobori, Takashi
AU - Linden, C. Gerard van der
AU - Loo, Eibertus N. van
AU - Jellen, Eric N.
AU - Maughan, Peter J.
AU - Tester, Mark A.
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Research reported in this publication was supported by the King Abdullah University of Science and Technology (KAUST), by USDA/NIFA-REEIS grant #2012-51300-20100 (WSU/BYU), by NSF grant #1339412, and by a grant from the German Research Foundation, DFG (grant no. JU205/24-1). We thank T. Ramaraj from the National Center for Genomic Resources (Santa Fe) for his bioinformatics assistance, O. Mohammed Eid Alharbi at the KAUST Imaging and Characterization Laboratory for generating SEM images, K. Zemmouri at the KAUST Greenhouse for plant care, and H. Ho (Heno) Hwang and I. D. Gromicho at the KAUST Academic Writing Department for assistance with quinoa illustrations and photographs. We also thank H. Štorchová, F. Morton, D. Bertero, F. Fuentes and D. Brenner of USDA-ARS-NPGS for their assistance in providing seeds.
PY - 2017/2/8
Y1 - 2017/2/8
N2 - Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome-contact and genetic maps. We also report the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identification of sub-genomes in quinoa, and reduced-coverage genome sequences for 22 other samples of the allotetraploid goosefoot complex. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and a premature stop codon in sweet quinoa strains. These genomic resources are an important first step towards the genetic improvement of quinoa.
AB - Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome-contact and genetic maps. We also report the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identification of sub-genomes in quinoa, and reduced-coverage genome sequences for 22 other samples of the allotetraploid goosefoot complex. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and a premature stop codon in sweet quinoa strains. These genomic resources are an important first step towards the genetic improvement of quinoa.
UR - http://hdl.handle.net/10754/622874
UR - http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21370.html
UR - http://www.scopus.com/inward/record.url?scp=85014835664&partnerID=8YFLogxK
U2 - 10.1038/nature21370
DO - 10.1038/nature21370
M3 - Article
C2 - 28178233
VL - 542
SP - 307
EP - 312
JO - Nature
JF - Nature
SN - 0028-0836
IS - 7641
ER -