The genome of Aiptasia, a sea anemone model for coral symbiosis

Sebastian Baumgarten, Oleg Simakov, Lisl Y. Esherick, Yi Jin Liew, Erik M. Lehnert, Craig Michell, Yong Li, Elizabeth A. Hambleton, Annika Guse, Matt E. Oates, Julian Gough, Virginia M. Weis, Manuel Aranda, John R. Pringle, Christian R. Voolstra

Research output: Contribution to journalArticlepeer-review

201 Scopus citations

Abstract

The most diverse marine ecosystems, coral reefs, depend upon a functional symbiosis between a cnidarian animal host (the coral) and intracellular photosynthetic dinoflagellate algae. The molecular and cellular mechanisms underlying this endosymbiosis are not well understood, in part because of the difficulties of experimental work with corals. The small sea anemone Aiptasia provides a tractable laboratory model for investigating these mechanisms. Here we report on the assembly and analysis of the Aiptasia genome, which will provide a foundation for future studies and has revealed several features that may be key to understanding the evolution and function of the endosymbiosis. These features include genomic rearrangements and taxonomically restricted genes that may be functionally related to the symbiosis, aspects of host dependence on alga-derived nutrients, a novel and expanded cnidarian-specific family of putative pattern-recognition receptors that might be involved in the animal–algal interactions, and extensive lineage-specific horizontal gene transfer. Extensive integration of genes of prokaryotic origin, including genes for antimicrobial peptides, presumably reflects an intimate association of the animal–algal pair also with its prokaryotic microbiome.
Original languageEnglish (US)
Pages (from-to)11893-11898
Number of pages6
JournalProceedings of the National Academy of Sciences
Volume112
Issue number38
DOIs
StatePublished - Aug 31 2015

Fingerprint

Dive into the research topics of 'The genome of Aiptasia, a sea anemone model for coral symbiosis'. Together they form a unique fingerprint.
  • Exaiptasia diaphana isolate:CC7 Genome sequencing and assembly

    Baumgarten, S. (Creator), Simakov, O. (Creator), Esherick, L. Y. (Creator), Liew, Y. J. (Creator), Lehnert, E. M. (Creator), Michell, C. (Creator), Li, Y. (Creator), Hambleton, E. A. (Creator), Guse, A. (Creator), Oates, M. E. (Creator), Gough, J. (Creator), Weis, V. M. (Creator), Aranda, M. (Creator), Pringle, J. R. (Creator), Voolstra, C. R. (Creator), Simakov, O. (Creator), Esherick, L. Y. (Creator), Lehnert, E. M. (Creator), Hambleton, E. A. (Creator), Guse, A. (Creator), Oates, M. E. (Creator), Gough, J. (Creator), Weis, V. M. (Creator) & Pringle, J. R. (Creator), NCBI, Oct 28 2015

    Dataset

Cite this