The Dual Role of Benzophenone in Visible-Light/Nickel Photoredox-Catalyzed C−H Arylations: Hydrogen-Atom Transfer and Energy Transfer

Abhishek Dewanji, Patricia E. Krach, Magnus Rueping

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

A dual catalytic protocol for the direct arylation of non-activated C(sp3)−H bonds has been developed. Upon photochemical excitation, the excited triplet state of a diaryl ketone photosensitizer abstracts a hydrogen atom from an aliphatic C−H bond. This inherent reactivity was exploited for the generation of benzylic radicals which subsequently enter a nickel catalytic cycle, accomplishing the benzylic arylation.
Original languageEnglish (US)
Pages (from-to)3566-3570
Number of pages5
JournalAngewandte Chemie International Edition
Volume58
Issue number11
DOIs
StatePublished - Feb 18 2019

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