The convergent route to globular dendritic macromolecules: A versatile approach to precisely functionalized three-dimensional polymers and novel block copolymers

Jean Frechet, Craig J. Hawker, Karen L. Wooley

Research output: Contribution to journalArticlepeer-review

93 Scopus citations

Abstract

The convergent growth approach to dendritic macromolecules is a versatile method for the preparation of globular molecules with highly controlled three-dimensional architectures. The method, inspired from a classical organic disconnection approach, starts growth of the globular dendrimer at what will become its chain-ends and proceeds toward what will become its center. The convergent growth has been applied to the preparation of a number of unconventional dendritic block copolymers as well as hybrid globular-linear copolymers that are not readily accessed by other routes. Control of the chemistry and the precise location of the chain-ends in convergent dendrimers is essential for the preparation of micellar, amphiphilic, dipolar, or other structures that may be useful in applications as varied as drug delivery and molecular devices.

Original languageEnglish (US)
Pages (from-to)1627-1645
Number of pages19
JournalJournal of Macromolecular Science, Part A
Volume31
Issue number11
DOIs
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemistry(all)
  • Polymers and Plastics
  • Materials Chemistry

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