Suzuki-Miyaura cross-coupling reactions in aqueous media: Green and sustainable syntheses of biaryls

Vivek Polshettiwar, Audrey Decottignies, Christophe Len, Aziz Fihri

Research output: Contribution to journalArticlepeer-review

297 Scopus citations

Abstract

Carbon-carbon cross-coupling reactions are among the most important processes in organic chemistry, and Suzuki-Miyaura reactions are among the most widely used protocols for the formation of carbon-carbon bonds. These reactions are generally catalyzed by soluble palladium complexes with various ligands. However, the use of toxic organic solvents remains a scientific challenge and an aspect of economical and ecological relevance. This Review will summarize various recently developed significant methods by which the Suzuki-Miyaura coupling was conducted in aqueous media, and analyzes if they are "real green" protocols. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original languageEnglish (US)
Pages (from-to)502-522
Number of pages21
JournalChemSusChem
Volume3
Issue number5
DOIs
StatePublished - Feb 28 2010

ASJC Scopus subject areas

  • Energy(all)
  • Environmental Chemistry
  • Materials Science(all)
  • Chemical Engineering(all)

Fingerprint Dive into the research topics of 'Suzuki-Miyaura cross-coupling reactions in aqueous media: Green and sustainable syntheses of biaryls'. Together they form a unique fingerprint.

Cite this