Superhydrophobic surfaces allow probing of exosome self organization using X-ray scattering

Angelo Accardo, Luca Tirinato, Davide Altamura, Teresa Sibillano, Cinzia Giannini, Christian Riekel, Enzo M. Di Fabrizio

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Drops of exosome dispersions from healthy epithelial colon cell line and colorectal cancer cells were dried on a superhydrophobic PMMA substrate. The residues were studied by small- and wide-angle X-ray scattering using both a synchrotron radiation micrometric beam and a high-flux table-top X-ray source. Structural differences between healthy and cancerous cells were detected in the lamellar lattices of the exosome macro-aggregates. © 2013 The Royal Society of Chemistry.
Original languageEnglish (US)
Pages (from-to)2295
JournalNanoscale
Volume5
Issue number6
DOIs
StatePublished - 2013

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: The authors are grateful for the SEED project "X-ray synchrotron class rotating anode microsource for the structural micro imaging of nanomaterials and engineered biotissues (XMI-LAB)" - IIT Protocol no. 21537 of 23/12/2009 and the FIRB 2009/2010 project "Rete integrata per la Nano Medicina (RINAME)" - RBAP114AMK_006. Rocco Lassandro and Giuseppe Chita are acknowledged for the technical support.

ASJC Scopus subject areas

  • Materials Science(all)

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