Study of sample dispersion mechanisms in an electroosmotically pumped microchannel

B. Debusschere*, H. Najm, A. Matta, O. Knio, R. Ghanem, O. Le Maître

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations


This paper presents detailed simulations of electroosmotic microchannel flow to study the effect of species charge, chemical reaction and random ζ potential variability on both elektrokinetic and hydrodynamic dispersion. The physical model used accounts for the coupled nature of momentum, species transport and reactions, as well as the electrostatic field. The chemistry model accounts for pH-dependent protein labeling reactions as well as detailed buffer electrochemistry. Using polynomical chaos expansions, the model also accounts for stochastic ζ potential variability due to heterogeneous wall surface properties. The results show that dispersion increases for higher species charges and for larger variability in ζ. The dispersion also depends mildly on the correlation length of the ζ potential variability.

Original languageEnglish (US)
Title of host publication2003 Nanotechnology Conference and Trade Show - Nanotech 2003
EditorsM. Laudon, B. Romanowicz
Number of pages4
StatePublished - 2003
Externally publishedYes
Event2003 Nanotechnology Conference and Trade Show - Nanotech 2003 - San Francisco, CA, United States
Duration: Feb 23 2003Feb 27 2003


Other2003 Nanotechnology Conference and Trade Show - Nanotech 2003
CountryUnited States
CitySan Francisco, CA


  • Labeling
  • Microchannel
  • Polynomial chaos
  • Sample dispersion
  • Simulation

ASJC Scopus subject areas

  • Engineering(all)

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