StrigoQuant: A genetically encoded biosensor for quantifying strigolactone activity and specificity

S. L. Samodelov, H. M. Beyer, X. Guo, M. Augustin, K.-P. Jia, Lina Baz, O. Ebenho h, P. Beyer, W. Weber, Salim Al-Babili, M. D. Zurbriggen

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Strigolactones are key regulators of plant development and interaction with symbiotic fungi; however, quantitative tools for strigolactone signaling analysis are lacking. We introduce a genetically encoded hormone biosensor used to analyze strigolactone-mediated processes, including the study of the components involved in the hormone perception/signaling complex and the structural specificity and sensitivity of natural and synthetic strigolactones in Arabidopsis, providing quantitative insights into the stereoselectivity of strigolactone perception. Given the high specificity, sensitivity, dynamic range of activity, modular construction, ease of implementation, and wide applicability, the biosensor StrigoQuant will be useful in unraveling multiple levels of strigolactone metabolic and signaling networks.
Original languageEnglish (US)
Pages (from-to)e1601266
JournalScience Advances
Volume2
Issue number11
DOIs
StatePublished - Nov 4 2016

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