Spider silk as a load bearing biomaterial: Tailoring mechanical properties via structural modifications

Cameron P. Brown, Federico Rosei, Enrico Traversa, Silvia Licoccia

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Spider silk shows great potential as a biomaterial: in addition to biocompatibility and biodegradability, its strength and toughness are greater than native biological fibres (e.g. collagen), with toughness exceeding that of synthetic fibres (e.g. nylon). Although the ultimate tensile strength and toughness at failure are unlikely to be limiting factors, its yield strain of 2% is insufficient, particularly for biomedical application because of the inability to mimic the complex ultrastructure of natural tissues with current tissue engineering approaches. To harness the full potential of spider silk as a biomaterial, it is therefore necessary to increase its yield strain. In this paper, we discuss the means by which the mechanical properties of spider silk, particularly the yield strain, can be optimized through structural modifications.

Original languageEnglish (US)
Pages (from-to)870-876
Number of pages7
JournalNanoscale
Volume3
Issue number3
DOIs
StatePublished - Mar 1 2011

ASJC Scopus subject areas

  • Materials Science(all)

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