Single-nucleotide polymorphisms in Rv2629 are specific for mycobacterium tuberculosis genotypes Beijing and Ghana but Not associated with rifampin resistance

Susanne Homolka, Claudio Köser, John Archer, Sabine Rüsch-Gerdes, Stefan Niemann*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Sequence analysis of 58 multidrug-resistant Mycobacterium tuberculosis complex strains from Germany and 55 susceptible strains from a reference collection comprising major phylogenetic lineages confirmed that variations in Rv2629, 191A/C and 965C/T, are specific for genotypes Beijing and Ghana, respectively, but not involved in the development of rifampin (rifampicin) resistance.

Original languageEnglish (US)
Pages (from-to)223-226
Number of pages4
JournalJournal of Clinical Microbiology
Volume47
Issue number1
DOIs
StatePublished - Jan 1 2009

ASJC Scopus subject areas

  • Microbiology (medical)

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