Shedding light on Brønsted acid catalysis-a photocyclization- reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow

Hsuan Hung Liao, Chien Chi Hsiao, Erli Sugiono, Magnus Rueping*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

A new asymmetric photocyclization-reduction cascade employing readily available aminochalcones has been developed. The reaction sequence has been achieved by unifying photochemistry and asymmetric Brønsted acid catalysis and involves photocyclization followed by Brønsted acid catalyzed enantioselective hydrogenation in batch and flow.

Original languageEnglish (US)
Pages (from-to)7953-7955
Number of pages3
JournalChemical Communications
Volume49
Issue number72
DOIs
StatePublished - Sep 18 2013

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Shedding light on Brønsted acid catalysis-a photocyclization- reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow'. Together they form a unique fingerprint.

Cite this