Self-Assembled Peptide Nanostructures for Regenerative Medicine and Biology

Ming Ni*, Charlotte Hauser

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

Peptides are intriguing building blocks for a variety of applications in bionanotechnology. They can self-assemble into many forms of nanostructures. In this chapter, we focus on peptide nanofibers and nanotubes. Their design principles are presented and their applications as tissue engineering scaffolds, drug delivery vehicles and therapeutics are illustrated. We also describe the nanofibers derived from a novel class of ultrashort self-assembling peptides. These ultrashort self-assembling peptides contain three to seven natural aliphatic amino acids and can form hydrogels with biocompatibility, high thermal stability and high mechanical strength. They hold great potential for various biotechnological and industrial applications.

Original languageEnglish (US)
Title of host publicationMicro and Nanofabrication Using Self-Assembled Biological Nanostructures
PublisherElsevier Inc.
Pages63-90
Number of pages28
ISBN (Electronic)9780323296526
ISBN (Print)9780323296427
DOIs
StatePublished - Sep 10 2014

Keywords

  • Drug delivery vehicles
  • Peptide nanofibers
  • Peptide nanotubes
  • Peptide therapeutics
  • Tissue engineering scaffolds
  • Ultrashort peptides

ASJC Scopus subject areas

  • Engineering(all)

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