Selective import of biomolecules through nanopored silicon nitride membranes

Manola Moretti*, Enzo Di Fabrizio, Francesco De Angelis, Giuseppe Firrao

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Selective transport of molecules through membrane is a prerogative of biological systems that is still far from being matched by nanoscale human manufacturing. Here we report our attempt to define a system based on pored silicon nitride membranes and mobile transporters for the selective recognition and import of nanosized objects (proteins, quantum dots, latex particles) from an external compartment. The system uses paramagnetic beads, modified to recognize specific target molecules, which are delivered to arrays of precisely milled pores. After capture of their target, the loaded transporters are removed from the pore and replaced. Prototypes that make use of electrophoretic or electromagnetic forces to mobilize the beads have been constructed and evaluated.

Original languageEnglish (US)
Title of host publicationULIS 2008 - 9th International Conference on ULtimate Integration of Silicon
Pages49-52
Number of pages4
DOIs
StatePublished - Aug 14 2008
Event9th International Conference on ULtimate Integration of Silicon, ULIS 2008 -
Duration: Mar 13 2008Mar 14 2008

Publication series

NameULIS 2008 - 9th International Conference on ULtimate Integration of Silicon

Other

Other9th International Conference on ULtimate Integration of Silicon, ULIS 2008
Period03/13/0803/14/08

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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