Roles for noncoding RNAs in cell-fate determination and regeneration

Mo Li, Juan Carlos Izpisua Belmonte

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Cellular fate is determined by transcriptional networks and epigenetic states. In addition to protein factors, noncoding RNAs (ncRNAs), particularly microRNAs and long ncRNAs, are able to remodel transcriptional circuits and reshape epigenetic landscapes. Here we draw upon recent findings to discuss the emerging roles of these ncRNAs in cellular reprogramming, transdifferentiation and organ regeneration.

Original languageEnglish (US)
Pages (from-to)2-4
Number of pages3
JournalNature Structural and Molecular Biology
Volume22
Issue number1
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

Fingerprint

Dive into the research topics of 'Roles for noncoding RNAs in cell-fate determination and regeneration'. Together they form a unique fingerprint.

Cite this