Re-infection with different SARS-CoV-2 clade and prolonged viral shedding in a patient with hematopoietic stem cell transplantation: SARS-CoV-2 Re-infection with different clade.

Abeer N Alshukairi, Sherif A El-Kafrawy, Ashraf Dada, Mohamed Yasir, Amani H Yamani, Mohammed F Saeedi, Ahmed Aljohaney, Naif I AlJohani, Husam A Bahaudden, Intikhab Alam, Takashi Gojobori, Aleksandar Radovanovic, Thamir A Alandijany, Norah A Othman, Tagreed L Alsubhi, Ahmed M Hassan, Ahmed M Tolah, Jaffar A Al-Tawfiq, Alimuddin Zumla, Esam I Azhar

Research output: Contribution to journalArticlepeer-review

Abstract

Immunocompromised patients who have SARS-CoV-2 infection pose many clinical and public health challenges. We describe a patient with hematopoietic stem cell transplantation and lymphoma with protracted illness requiring 3 consecutive hospital admissions. Whole genome sequencing confirmed two different SARS-CoV-2 clades. Clinical management issues, and unanswered questions arising are discussed.

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

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