Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen

An Qi Yang, Dong Wang, Xiang Wang, Yu Han, Xue Bin Ke, Hong Jun Wang, Xi Zhou*, Lei Ren

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

A versatile approach for highly sensitive surface-enhanced Raman scattering (SERS) detection of prostate specific antigen (PSA) has been developed based on immune recognition assisted fabrication of gold nanorods (AuNRs) assemblies. Compared with the typical enzyme-linked immunosorbent assay, this SERS immunoassay strategy showed an obviously enhanced sensitivity. The SERS immunoassay for PSA detection has also been successfully applied in diluted human serum samples, showing the promising potential for early diagnosis of diseases in clinical application.

Original languageEnglish (US)
Pages (from-to)38354-38360
Number of pages7
JournalRSC Advances
Volume5
Issue number48
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Fingerprint Dive into the research topics of 'Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen'. Together they form a unique fingerprint.

Cite this