Quantitative Fluorescence Sensing Through Highly Autofluorescent, Scattering, and Absorbing Media Using Mobile Microscopy

Zoltán Göröcs, Yair Rivenson, Hatice Ceylan Koydemir, Derek Tseng, Tamara L. Troy, Vasiliki Demas, Aydogan Ozcan

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Compact and cost-effective systems for in vivo fluorescence and near-infrared imaging in combination with activatable reporters embedded inside the skin to sample interstitial fluid or blood can enable a variety of biomedical applications. However, the strong autofluorescence of human skin creates an obstacle for fluorescence-based sensing. Here we introduce a method for quantitative fluorescence sensing through highly autofluorescent, scattering, and absorbing media. For this, we created a compact and cost-effective fluorescence microscope weighing
Original languageEnglish (US)
Pages (from-to)8989-8999
Number of pages11
JournalACS Nano
Volume10
Issue number9
DOIs
StatePublished - Sep 19 2016
Externally publishedYes

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