Probing droplets with biological colloidal suspensions on smart surfaces by synchrotron radiation micro- and nano-beams

Giovanni Marinaro, Angelo Accardo, Núria Benseny-Cases, Manfred C. Burghammer, Hiram A. Castillo-Michel, Marine Cotte, Silvia Dante, Francesco De De Angelis, Emanuela Di Cola, Enzo M. Di Fabrizio, C. Hauser, Christian Riekel

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Droplets with colloidal biological suspensions evaporating on substrates with defined wetting properties generate confined environments for initiating aggregation and self-assembly processes. We describe smart micro- and nanostructured surfaces, optimized for probing single droplets and residues by synchrotron radiation micro- and nanobeam diffraction techniques. Applications are presented for Ac-IVD and β-amyloid (1-42) peptides capable of forming cross-β sheet structures. Complementary synchrotron radiation FTIR microspectroscopy addresses secondary structure formation. The high synchrotron radiation source brilliance enables fast raster-scan experiments. © 2015 Elsevier Ltd.
Original languageEnglish (US)
Pages (from-to)57-63
Number of pages7
JournalOptics and Lasers in Engineering
Volume76
DOIs
StatePublished - Apr 8 2015

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering
  • Mechanical Engineering

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