Preparation and determination of X-ray-crystal and NMR-solution structures of γ2,3,4-peptides

D. Seebach*, M. Brenner, Magnus Rueping, B. Schweizer, B. Jaun

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

102 Scopus citations

Abstract

(R,R,R)-γ-Amino acids with side chains in the 2-, 3-, and 4-positions, prepared by addition of acyloxazolidinones to a nitroolefin and hydrogenation, have been coupled to γ-tetra-, and γ-hexapeptides which are shown to form (M)-2.614 helices in the crystal state and in MeOH solution.

Original languageEnglish (US)
Pages (from-to)207-208
Number of pages2
JournalChemical Communications
Issue number2
DOIs
StatePublished - Jan 21 2001

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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