Several recent studies have demonstrated that pluri-potent progenitor cells (stem cells) are present and divide in the central nervous system in adult life. This neurogenesis occurs in specific areas of the brain, and can be enhanced by learning, but also by cerebral lesions. Cerebral ischemia for instance has been shown to increase neurogenesis. Furthermore, newly formed neurons seem to be able to replace the injured neurons functionally. These results are encouraging, and although a more refined understanding of the system is required, a therapeutical use of progenitor cells in the case of neuronal loss in neurodegenerative diseases, traumatic brain injury and cerebral ischemia can be envisioned in the future.
|Translated title of the contribution||Post-ischemic neuronal regeneration: A potential for therapy|
|Number of pages||6|
|Journal||Medecine et Hygiene|
|State||Published - Oct 18 2000|
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