Régénération cellulaire neuronale post-ischémique: Potentiel thérapeutique

Translated title of the contribution: Post-ischemic neuronal regeneration: A potential for therapy

J. Badaut*, L. Hirt, L. Regli, J. G. Villemure, J. Bogousslavsky, P. J. Magistretti

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Several recent studies have demonstrated that pluri-potent progenitor cells (stem cells) are present and divide in the central nervous system in adult life. This neurogenesis occurs in specific areas of the brain, and can be enhanced by learning, but also by cerebral lesions. Cerebral ischemia for instance has been shown to increase neurogenesis. Furthermore, newly formed neurons seem to be able to replace the injured neurons functionally. These results are encouraging, and although a more refined understanding of the system is required, a therapeutical use of progenitor cells in the case of neuronal loss in neurodegenerative diseases, traumatic brain injury and cerebral ischemia can be envisioned in the future.

Translated title of the contributionPost-ischemic neuronal regeneration: A potential for therapy
Original languageFrench
Pages (from-to)2032-2037
Number of pages6
JournalMedecine et Hygiene
Volume58
Issue number2318
StatePublished - Oct 18 2000
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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