Polymeric monolithic stationary phases for capillary eletrochromatography

Emily F. Hilder, Frantisek Svec, Jean Frechet*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

127 Scopus citations

Abstract

This review summarizes the contributions of a number of groups working in the rapidly growing area of monolithic columns for capillary electrochromatography (CEC), with a focus on those prepared from synthetic polymers. Monoliths have quickly become a well-established stationary phase format in the field of CEC. The simplicity of their in situ preparation method as well as the good control over their porous properties and surface chemistries make the monolithic separation media an attractive alternative to capillary columns packed with particulate materials. A wide variety of approaches as well as materials used for the preparation of the monolithic stationary phases are detailed. Their excellent chromatographic performance is demonstrated by numerous separations of different analytes.

Original languageEnglish (US)
Pages (from-to)3934-3953
Number of pages20
JournalElectrophoresis
Volume23
Issue number22-23
DOIs
StatePublished - Nov 1 2002

Keywords

  • Capillary eletrochromatography
  • Column technology
  • Monolith
  • Porous polymer
  • Review

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry

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