Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA

Ye Liu*, De Cheng Wu, Wei De Zhang, Xuan Jiang, Chao Bin He, Tai Shung Chung, Suat Hong Goh, Kam W. Leong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

321 Scopus citations

Abstract

(Figure Presented) DNA hits the wall: DNA is immobilized securely onto the surface of multiwalled carbon nanotubes through electrostatic interactions with grafted polyethylenimine (PEI; see picture). The polyethylenimine-graft multiwalled carbon nanotubes carrying DNA show transfection efficiency for DNA delivery similar to or even several times higher than PEI.

Original languageEnglish (US)
Pages (from-to)4782-4785
Number of pages4
JournalAngewandte Chemie - International Edition
Volume44
Issue number30
DOIs
StatePublished - Jul 25 2005
Externally publishedYes

Keywords

  • Amines
  • Carbon nanotubes
  • DNA
  • Gene technology
  • Polymerization

ASJC Scopus subject areas

  • Chemistry(all)

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