Poly-ethers from Winogradskyella poriferorum: Antifouling potential, time-course study of production and natural abundance

Swagatika Dash, Yasuyuki Nogata, Xiaojian Zhou, Yifan Zhang, Ying Xü, Xian Rong Guo, Xixiang Zhang, Pei-Yuan Qian

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

A sponge-associated bacterium, Winogradskyella poriferorum strain UST030701-295T was cultured up to 100l for extraction of antifouling bioactive compounds. Five poly-ethers were isolated and partially characterized based on nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS); two of them showed inhibitory effects on biofilm formation of marine bacteria and larval settlement of macro-foulers but did not produce any adverse effects on the phenotypes of zebra fish embryos at a concentration of 5μgml -1. The effect of culture duration on the production of the poly-ethers and the bioactivity of the relevant extracts was monitored over a period of 12days. The total crude poly-ether production increased from day 2 to day 5 and the highest bioactivity was observed on day 3. The poly-ethers were found to be localized in the cellular fraction of the extracts, implying their natural occurrence. The potent bioactivity of these poly-ethers together with their high natural abundance in bacteria makes them promising candidates as ingredients in antifouling applications. © 2011 Elsevier Ltd.
Original languageEnglish (US)
Pages (from-to)7532-7537
Number of pages6
JournalBioresource Technology
Volume102
Issue number16
DOIs
StatePublished - Aug 2011

ASJC Scopus subject areas

  • Bioengineering
  • Environmental Engineering
  • Waste Management and Disposal

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