Pictet-Spengler synthesis of some thiophene[c]-fused β-carbolines

Kayed A. Abu Safieh, Basem Moosa, Mustafa M. El-Abadelah, Salim S. Sabri, Wolfgang Voelter*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

5-(Substituted) thieno[2′,3′:5,6]pyrido[3,4-b]indoles were synthesized via cyclocondensation of 3-(3-aminothien-2-yl)indole with the appropriate aldehyde in the presence of boron trifluoride etherate under Pictet-Spengler reaction conditions. The constitution of the new compounds is evidenced from analytical and spectral (NMR and MS) data.

Original languageEnglish (US)
Pages (from-to)147-151
Number of pages5
JournalMonatshefte fur Chemie
Volume139
Issue number2
DOIs
StatePublished - Feb 1 2008

Keywords

  • 3-(3-Aminothien-2-yl)indole
  • Pictet-Spengler reaction
  • Thieno[2,3-c]-β- carbolines

ASJC Scopus subject areas

  • Chemistry(all)

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