Photoredox catalysis as an efficient tool for the aerobic oxidation of amines and alcohols: Bioinspired demethylations and condensations

Magnus Rueping*, Carlos Vila, Anna Szadkowska, Rene M. Koenigs, Jeanne Fronert

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

111 Scopus citations

Abstract

Tertiary amines were readily converted into secondary amines through a photoredox-catalyzed N-demethylation, a bioinspired procedure that resembles nature's enzymatic pathways. Furthermore, the selective oxidation of primary amines as well as primary and secondary alcohols was achieved using photoredox catalysis. The protocols feature low catalyst loadings (1-2 mol %) and offer access to diverse imines and carbonyl compounds.

Original languageEnglish (US)
Pages (from-to)2810-2815
Number of pages6
JournalACS Catalysis
Volume2
Issue number12
DOIs
StatePublished - Dec 7 2012

Keywords

  • N-demethylation
  • cross dehydrogenative coupling
  • organic dye
  • oxidation
  • oxygen
  • visible light

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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