Optical force on diseased blood cells: Towards the optical sorting of biological matter

J. S. Totero Gongora, Andrea Fratalocchi

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

By employing a series of massively parallel ab-initio simulations, we study how optical forces act on biological matter subject to morphological disease. As a representative case study, we here consider the case of Plasmodium falciparum on red blood cells (RBC) illuminated by a monochromatic plane wave. Realistic parameters for the geometry and the refractive index are then taken from published experiments. In our theoretical campaign, we study the dependence of the optical force on the disease stage for different incident wavelengths. We show that optical forces change significantly with the disease, with amplitude variation in the hundreds of pN range. Our results open up new avenues for the design of new optical systems for the treatment of human disease. © 2015 Elsevier Ltd.
Original languageEnglish (US)
Pages (from-to)40-44
Number of pages5
JournalOptics and Lasers in Engineering
Volume76
DOIs
StatePublished - May 21 2015

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering
  • Mechanical Engineering

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