Optical fiber tweezers fabricated by two photon lithography

C. Liberale*, E. Di Fabrizio, G. Cojoc, G. Perozziello, P. Candeloro, F. Bragheri, L. Ferrara, P. Minzioni, I. Cristiani

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Optical tweezers are unique tools for manipulation and analysis of single cells. The development of miniaturised trapping systems is a key issue as they could reduce system complexity and improve usability. In addition miniaturised traps can be easily combined with microfluidic circuits and they could open the way to in-vivo applications. In Ref. [1], tweezers based on an optical fiber bundle were proposed, where the equivalent effect of a high NA focusing system was obtained by total-internal-reflection (TIR) at the interface between fibers and surrounding-medium. The optical beams' deflection obtained through TIR makes them converging in the same spatial point that corresponds to the trap. Such a fiber-based approach is in principle extremely powerful as it doesn't require any critical alignment and, besides miniaturization, it opens the way to the realization of a multipurpose tool including additional optical functions for analysis and actuation of the trapped cells.

Original languageEnglish (US)
Title of host publication2011 Conference on Lasers and Electro-Optics Europe and 12th European Quantum Electronics Conference, CLEO EUROPE/EQEC 2011
DOIs
StatePublished - 2011
Externally publishedYes
Event2011 Conference on Lasers and Electro-Optics Europe and 12th European Quantum Electronics Conference, CLEO EUROPE/EQEC 2011 - Munich, Germany
Duration: May 22 2011May 26 2011

Other

Other2011 Conference on Lasers and Electro-Optics Europe and 12th European Quantum Electronics Conference, CLEO EUROPE/EQEC 2011
CountryGermany
CityMunich
Period05/22/1105/26/11

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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