We propose an efficient numerical technique for calibrating the mathematical model that describes the singleevent related brain response when fMRI measurements are given. This method employs a regularized Newton technique in conjunction with a Kalman filtering procedure. We have applied this method to estimate the biophysiological parameters of the Balloon model that describes the hemodynamic brain responses. Illustrative results obtained with both synthetic and real fMRI measurements are presented. © 2014 IEEE.
|Original language||English (US)|
|Title of host publication||2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society|
|Publisher||Institute of Electrical and Electronics Engineers (IEEE)|
|Number of pages||4|
|State||Published - Aug 2014|