Non-linear modeling of active biohybrid materials

C. Paetsch, A. Dorfmann

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Recent advances in engineered muscle tissue attached to a synthetic substrate motivate the development of appropriate constitutive and numerical models. Applications of active materials can be expanded by using robust, non-mammalian muscle cells, such as those of Manduca sexta. In this study, we propose a model to assist in the analysis of biohybrid constructs by generalizing a recently proposed constitutive law for Manduca muscle tissue. The continuum model accounts (i) for the stimulation of muscle fibers by introducing multiple stress-free reference configurations for the active and passive states and (ii) for the hysteretic response by specifying a pseudo-elastic energy function. A simple example representing uniaxial loading-unloading is used to validate and verify the characteristics of the model. Then, based on experimental data of muscular thin films, a more complex case shows the qualitative potential of Manduca muscle tissue in active biohybrid constructs. © 2013 Elsevier Ltd. All rights reserved.
Original languageEnglish (US)
Pages (from-to)105-114
Number of pages10
JournalInternational Journal of Non-Linear Mechanics
Volume56
DOIs
StatePublished - Nov 2013
Externally publishedYes

Fingerprint Dive into the research topics of 'Non-linear modeling of active biohybrid materials'. Together they form a unique fingerprint.

Cite this