New CSPs based on peptidomimetics: Efficient chiral selectors in enantioselective separations

M. Isabel Burguete, Jean Frechet, Eduardo García-Verdugo, Miroslav Janco, Santiago V. Luis*, Frantisek Svec, María J. Vicent, Mingcheng Xu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Two different families of peptidomimetics have been synthesized and used as chiral selectors for enantioselective chromatography. The functionalization of compounds with multiple nitrogen atoms allows their use in the preparation of chiral stationary phases (CSPs), with acrylic or styril comonomers, in both bead and monolithic formats. Some of these separation media, having the appropriate morphological properties for their use in chromatographic columns, were able to efficiently discriminate enantiomers of aminoacid derivatives and pharmaceuticals such as Oxazepam.

Original languageEnglish (US)
Pages (from-to)9-15
Number of pages7
JournalPolymer Bulletin
Volume48
Issue number1
DOIs
StatePublished - Dec 1 2002

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics
  • Polymers and Plastics
  • Materials Chemistry

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