Natriuretic peptides - A class of heterologous molecules in plants

Christoph Gehring*, H. R. Irving

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Immunological and physiological evidence suggests the presence of biologically active natriuretic peptide hormones (NPs) in plants. Evidence includes specific binding of rat atrial NP, [rANP (99-126)] to plant membranes and the promotion of cyclic guanosine-3′,5′-monophosphate (cGMP) mediated stomatal responses. Furthermore, anti-ANP affinity purifies biologically active plant immunoreactants (irPNPs) and a biologically active Arabidopsis thaliana irPNP (AtPNP-A) has been identified. AtPNP-A belongs to a novel class of molecules that share some similarity with the cell wall loosening expansins but do not contain the carbohydrate-binding wall anchor, thus suggesting that irPNPs and ANP are heterologues. We hypothesise that irPNP-like molecules have evolved from primitive glucanase-like molecules that have been recruited to become systemically mobile modulators of homeostasis acting via the plasma membrane. Such a function is compatible with localisation in the conductive tissue and the physiological and cellular modes of action of irPNPs reported to-date.

Original languageEnglish (US)
Pages (from-to)1318-1322
Number of pages5
JournalInternational Journal of Biochemistry and Cell Biology
Volume35
Issue number9
DOIs
StatePublished - Sep 1 2003

Keywords

  • Homeostasis
  • Natriuretic peptides
  • Plant hormones

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology

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