Nano-organocatalyst: magnetically retrievable ferrite-anchored glutathione for microwave-assisted Paal–Knorr reaction, aza-Michael addition, and pyrazole synthesis

Vivek Polshettiwar, Rajender S. Varma

Research output: Contribution to journalArticlepeer-review

186 Scopus citations

Abstract

Postsynthetic Surface modification of magnetic nanoparticles by glutathione imparts desirable chemical functionality and enables the generation of catalytic sites on the surfaces of ensuing organocatalysts. In this article, we discuss the developments, unique activity, and high selectivity of nano-organocatalysts for microwave-assisted Paal-Knorr reaction, aza-Michael addition, and pyrazole synthesis. Their insoluble character Coupled with paramagnetic nature enables easy separation of these nano-catalysts from the reaction mixture using external magnet, which eliminates the requirement of catalyst filtration. Published by Elsevier Ltd.
Original languageEnglish (US)
Pages (from-to)1091-1097
Number of pages7
JournalTetrahedron
Volume66
Issue number5
DOIs
StatePublished - Jan 2010
Externally publishedYes

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