Monodispersed polystyrene latex particles functionalized by the macromonomer technique. II. Application in immunodiagnosis

Sebastien Gibanel, Valerie Heroguez, Yves Gnanou, Esteban Aramendia, Alexander Bucsi, Jacqueline Forcada*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Monodispersed polymer colloids with aldehyde and acetal functionalities, introduced by the macromonomer technique, were synthesized by a two-step emulsion polymerization process. The latex samples so formed were chosen as the polymetric support to carry out covalent coupling with the antibody IgG anti-C reactive protein, to test the utility of the latex-protein complexes formed in immunoassays. More than the 45% of the initially linked protein was covalently coupled in the acetal latex samples.

Original languageEnglish (US)
Pages (from-to)494-499
Number of pages6
JournalPolymers for Advanced Technologies
Volume12
Issue number8
DOIs
StatePublished - Aug 2001

Keywords

  • Aldehyde and acetal functionality
  • Emulsion polymerization
  • Immunoassays
  • Latex-protein complexes
  • Macromonomers

ASJC Scopus subject areas

  • Polymers and Plastics

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