Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds

Vladmír S̆migol, Frantis̆ek S̆vec*, Ken Hosoya, Qing Wang, Jean M.J. Fréchet

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

132 Scopus citations

Abstract

The effects of initiator concentration, ionic strength of polymerization medium, polymerization temperature, and monomer/water phase ratio on particle size, particle size distribution and molecular weight of the resulting polymers prepared by an emulsifier‐free emulsion polymerization of styrene, methyl methacrylate and glycidyl methacrylate have been studied. Optimal conditions for preparation of uniformly sized polystyrene particles larger than 1 μm have been found. An attempt to synthesize monodisperse particles of similar size from methacrylate monomers and crosslinked particles has failed. It is shown that the swelling ability of “non‐activated” latex particles does not exceed 70 fold increase in the volume and strongly depends on the size of the original particles.

Original languageEnglish (US)
Pages (from-to)151-164
Number of pages14
JournalDie Angewandte Makromolekulare Chemie
Volume195
Issue number1
DOIs
StatePublished - Jan 1 1992
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)

Fingerprint

Dive into the research topics of 'Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds'. Together they form a unique fingerprint.

Cite this