TY - JOUR
T1 - Metal catalyzed cross-coupling of aryl and benzyl methyl sulfides
T2 - Nickel catalyzed Caryl-Csp3 and Csp3Csp3 bond formations
AU - Leiendecker, Matthias
AU - Chatupheeraphat, Adisak
AU - Rueping, Magnus
PY - 2015/4
Y1 - 2015/4
N2 - The functionalization of CAr-SMe and Csp3-SMe bonds by direct exchange of the sulfur atom with an activated sp3-carbon has been developed. Reactions with LiCH2SiMe3 in the presence of a Nickel catalyst proceed with good yields and allow the conversion of aryl and benzyl methyl sulfides to trimethylsilylated products which are valuable precursors for the synthesis of olefins, various alcohols and amines, diols and aromatic carboxylic acids.
AB - The functionalization of CAr-SMe and Csp3-SMe bonds by direct exchange of the sulfur atom with an activated sp3-carbon has been developed. Reactions with LiCH2SiMe3 in the presence of a Nickel catalyst proceed with good yields and allow the conversion of aryl and benzyl methyl sulfides to trimethylsilylated products which are valuable precursors for the synthesis of olefins, various alcohols and amines, diols and aromatic carboxylic acids.
UR - http://www.scopus.com/inward/record.url?scp=84940973368&partnerID=8YFLogxK
U2 - 10.1039/c5qo00001g
DO - 10.1039/c5qo00001g
M3 - Article
AN - SCOPUS:84940973368
VL - 2
SP - 350
EP - 353
JO - Organic Chemistry Frontiers
JF - Organic Chemistry Frontiers
SN - 2052-4110
IS - 4
ER -