Metal catalyzed cross-coupling of aryl and benzyl methyl sulfides: Nickel catalyzed Caryl-Csp3 and Csp3Csp3 bond formations

Matthias Leiendecker, Adisak Chatupheeraphat, Magnus Rueping*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

The functionalization of CAr-SMe and Csp3-SMe bonds by direct exchange of the sulfur atom with an activated sp3-carbon has been developed. Reactions with LiCH2SiMe3 in the presence of a Nickel catalyst proceed with good yields and allow the conversion of aryl and benzyl methyl sulfides to trimethylsilylated products which are valuable precursors for the synthesis of olefins, various alcohols and amines, diols and aromatic carboxylic acids.

Original languageEnglish (US)
Pages (from-to)350-353
Number of pages4
JournalOrganic Chemistry Frontiers
Volume2
Issue number4
DOIs
StatePublished - Apr 2015

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Metal catalyzed cross-coupling of aryl and benzyl methyl sulfides: Nickel catalyzed C<sub>aryl</sub>-Csp<sup>3</sup> and Csp<sup>3</sup>Csp<sup>3</sup> bond formations'. Together they form a unique fingerprint.

Cite this