Metagenomics-driven rapid diagnosis of an imported fatal case of rare amoebic meningoencephalitis

Qingtian Guan, Bushra Alhuthali, Sara Mfarrej, Magid Abdel Halim, Reem S Almaghrabi, Arnab Pain

Research output: Contribution to journalArticlepeer-review

Abstract

We identified Naegleria fowleri as the aetiologic agent from cerebrospinal fluid (CSF) of a patient with a travel history to Karachi. We demonstrate the benefit of metagenomics-based rapid diagnosis of primary amoebic meningoencephalitis (PAM) when routine clinical tests fail to provide a definitive diagnosis. We reconstructed the N. fowleri genome.
Original languageEnglish (US)
JournalJournal of Travel Medicine
DOIs
StatePublished - Nov 5 2021

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

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